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Anti-LXR alpha NR1H3 Rabbit Monoclonal Antibody

Anti-LXR alpha NR1H3 Rabbit Monoclonal Antibody

ArtNr	BOS-M03331
Hersteller	Boster
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, ICC
Clon	ABEB-14
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Oxysterols receptor LXR-alpha;Liver X receptor alpha;Nuclear receptor subfamily 1 group H member 3;NR1H3;LXRA;
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Manufacturers Product Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturers Research Category	Cancer, Cancer Metabolism, Cardiovascular, Cholesterol Metabolism, Co-Factors, Cofactors, Vitamins/Minerals, Epigenetics and Nuclear Signaling, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipid Signaling, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism of Lipids and Lipoproteins, Nuclear Receptors, Nuclear Signaling Pathways, Pathways and Processes, Signal Transduction, Signaling Pathway, Transcription
Short Description	Boster Bio Anti-LXR alpha NR1H3 Rabbit Monoclonal Antibody catalog # M03331. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-LXR alpha NR1H3 Rabbit Monoclonal Antibody catalog # M03331. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Gene Name	NR1H3
Application Details	WB 1:500-1:2000 ICC/IF 1:50-1:200 FC 1:50
Clonality	Monoclonal
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Immunogen	A synthesized peptide derived from human LXR alpha
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Oxysterols receptor LXR-alpha
Molecular Weight	50396 MW
Protein Function	Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand- binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half- sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920)..
Subcellular Localization	Nucleus.
Tissue Specificity	Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 13.09.2024

Express-Lieferung: 4 Tage sparen

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