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Anti-Mitochondrial dicarboxylate carrier/SLC25A10 Antibody Picoband® Europäischer Partner

ArtNr BOS-A10727-3
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody
Format Lyophilized
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations 1. Fiermonte, G., Dolce, V., Arrigoni, R., Runswick, M. J., Walker, J. E., Palmieri, F. Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family. Biochem. J. 344: 953-960, 1999.
2. Mizuarai, S., Miki, S., Araki, H., Takahashi, K., Kotani, H. Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis. J. Biol. Chem. 280: 32434-32441, 2005.
3. Pannone, E., Fiermonte, G., Dolce, V., Rocchi, M., Palmieri, F. Assignment of the human dicarboxylate carrier gene (DIC) to chromosome 17 band 17q25.3. Cytogenet. Cell Genet. 83: 238-239, 1998.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
At -20°C for one year from date of receipt.
After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.
Avoid repeated freezing and thawing.
Observed Molecular Weight
29-31 kDa
Calculated Molecular weight
29370 MW
Clonality
Polyclonal
Application Details
Western blot, 0.25-0.5 ?g/ml, Human, Rat

Immunohistochemistry(Paraffin-embedded Section), 2-5 ?g/ml, Human, Mouse, Rat

Immunofluorescence, 5 ?g/ml, Human

ELISA, 0.1-0.5 ?g/ml, -
Manufacturer - Gene Name
SLC25A10
Gene Full Name
NOVA alternative splicing regulator 2
Background
The mitochondrial dicarboxylate carrier (DIC) is an integral membrane protein encoded by the SLC25A10 gene in humans that catalyzes the transport of dicarboxylates such as malonate, malate, and succinate across the inner mitochondrial membrane in exchange for phosphate, sulfate, and thiosulfate by a simultaneous antiport mechanism, thus supplying substrates for the Krebs cycle, gluconeogenesis, urea synthesis, fatty acid synthesis, and sulfur metabolism. This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen
E.coli-derived human Mitochondrial dicarboxylate carrier/SLC25A10 recombinant protein (Position: Q37-Q276).
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Channels, Metabolism, Plasma Membrane, Signal Transduction
Protein Name
Aquaporin-6
Protein Function
May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.
Subcellular Localization
Nucleus.
Description
Boster Bio Anti-Mitochondrial dicarboxylate carrier/SLC25A10 Antibody Picoband® catalog # A10727-3. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Brain. Expression restricted to astrocytes.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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