Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody

HIF1a Antibody is a Rabbit Polyclonal antibody against HIF1a. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

HIF1A

This product is for research use only.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.