ArtNr |
ABC-AW5648-U100 |
Hersteller |
Abcepta
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
GARS, GlyRS, Diadenosine tetraphosphate synthetase, Glycyl-tRNA synthetase, AP-4-A synthetase, Glycine--tRNA ligase |
Lieferbar |
|
Primary Accession |
P41250 |
Antigen Type |
Synthesized Peptide |
Application |
WB |
Bio Background |
GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. |
Bio References |
Shiba K., Schimmel P.J. Biol. Chem. 269:30049-30055(1994) Antonellis A., Ellsworth R.E.Am. J. Hum. Genet. 72:1293-1299(2003) |
Clonality |
Polyclonal |
Gene ID |
2617 |
Gene Name |
|
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, Rat |
Legend image 1 |
All lanes : Anti-GARS Antibody (C-term) at1:4000 dilutionLane 1: NCI-H460 whole cell lysateLane 2: HT-1080 whole cell lysateLane 3: Jurkat whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 83 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:4000 |
Legend image 2 |
All lanes : Anti-GARS Antibody (C-term) at1:2000 dilutionLane 1: NCI-H460 whole cell lysateLane 2: HT-1080 whole cell lysateLane 3: Jurkat whole cell lysateLane 4: C6 whole cell lysateLane 5: Ramos whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 83 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 2 |
WB |
Dilution image 2 |
1:2000 |
Other Accession |
Q5RBL1 |
Isotype |
Rabbit Ig |
Calculated MW |
83166 |
Antigen Region |
706-739 |
Antigen Source |
HUMAN |
Target/Specificity |
This GARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-739 amino acids from the C-terminal region of human GARS. |
NCBI Accession |
NP_002038.2 |
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