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SOX2 Antibody (C-term)

SOX2 Antibody (C-term)

ArtNr	ABC-AW5343-U100
Hersteller	Abcepta
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SOX2, Transcription factor SOX-2
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Primary Accession	P48431
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Bio References	Stevanovic M., et al.Mamm. Genome 5:640-642(1994). Sadler L.A., et al.Submitted (DEC-1992) to the EMBL/GenBank/DDBJ databases. Fantes J., et al.Nat. Genet. 33:461-463(2003). Takahashi K., et al.Cell 131:861-872(2007). Rigbolt K.T., et al.Sci. Signal. 4:RS3-RS3(2011).
Clonality	Polyclonal
Gene ID	6657
Gene Name	SOX2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of lysates from F9, NCCIT cell line (from left to right), using SOX2 Antibody (C-term)(Cat. #AW5343). AW5343 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	P48430; P54231
Predicted	C, Sh
Isotype	Rabbit Ig
Calculated MW	34310
Antigen Region	282-316
Antigen Source	HUMAN
Target/Specificity	This SOX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2.

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ABC-AW5343-U100-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 04.10.2024

Express-Lieferung: 21 Tage sparen

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