ArtNr |
ABC-AW5153-U100 |
Hersteller |
Abcepta
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
HIST1H3A; H3FA; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l |
Lieferbar |
|
Primary Accession |
P68431 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. |
Bio References |
Lusic, M., et al., EMBO J. 22(24):6550-6561 (2003).Deng, L., et al., Virology 289(2):312-326 (2001).Deng, L., et al., Virology 277(2):278-295 (2000).El Kharroubi, A., et al., Mol. Cell. Biol. 18(5):2535-2544 (1998).Albig, W., et al., Hum. Genet. 101(3):284-294 (1997). |
Clonality |
Polyclonal |
Gene ID |
8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of lysate from Hela cell line, using Phospho-H3-pS10 Antibody (Cat. #AW5153). AW5153 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysate at 20ug. |
Type image 1 |
WB |
Dilution image 1 |
1:500 |
Legend image 2 |
Western blot analysis of lysate from Hela cell line, using Phospho-H3-pS10 Antibody (Cat. #AW5153). AW5153 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysate at 20ug. |
Type image 2 |
WB |
Dilution image 2 |
1:500 |
Predicted |
M, Rat, B |
Isotype |
Rabbit Ig |
Calculated MW |
15404 |
Antigen Region |
8-35 |
Antigen Source |
HUMAN |
Target/Specificity |
This HIST1H3B3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human HIST1H3B3. |
NCBI Accession |
NP_003520.1; NP_003521.2; NP_003522.1; NP_003523.1; NP_003524.1; NP_003525.1; NP_003526.1; NP_003527.1; NP_003528.1; NP_066298.1 |
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