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HDAC1 Antibody(C-term)

HDAC1 Antibody(C-term)

ArtNr	ABC-AW5103-U100
Hersteller	Abcepta
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	HDAC1; RPD3L1; Histone deacetylase 1
Lieferbar
Primary Accession	Q13547
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Bio References	Yang, Z., et al. Clin. Chem. Lab. Med. 48(12):1785-1791(2010) Grausenburger, R., et al. J. Immunol. 185(6):3489-3497(2010) Miller, K.M., et al. Nat. Struct. Mol. Biol. 17(9):1144-1151(2010) Brandt, S., et al. Int. J. Biochem. Cell Biol. 42(9):1472-1481(2010) Leone, V., et al. Oncogene 29(30):4341-4351(2010)
Clonality	Polyclonal
Gene ID	3065
Gene Name	HDAC1 (HGNC:4852)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, Rat
Legend image 1	Western blot analysis of lysates from Hela, K562 cell line, rat spleen tissue lysate (from left to right), using HDAC1 Antibody (C-term)(Cat. #AW5103). AW5103 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q4QQW4; O09106; Q32PJ8; NP_004955.2
Predicted	B, M
Isotype	Rabbit Ig
Calculated MW	55103
Antigen Region	421-450
Antigen Source	HUMAN
Target/Specificity	This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human HDAC1.
NCBI Accession	NP_004955.2

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ABC-AW5103-U100-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 04.10.2024

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