WDR4 Antibody (monoclonal) (M01)

Recombinant Protein

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.

Monoclonal

WDR4 {ECO:0000255|HAMAP-Rule:MF_03056, ECO:0000312|HGNC:HGNC:12756}

H

WB

WDR4 monoclonal antibody (M01), clone 1F9 Western Blot analysis of WDR4 expression in Hela S3 NE ( (Cat # AT4531a )

1:500~1000

WB

Immunoperoxidase of monoclonal antibody to WDR4 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1 ug/ml]

Detection limit for recombinant GST tagged WDR4 is approximately 1ng/ml as a capture antibody.

BC001074

Human: ~~ Positive

NP_001247403.1; NP_001247404.1; NP_001247405.1; NP_001247406.1; NP_061139.2; NP_387510.1

AAH01074

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq