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SPINLW1 Antibody (monoclonal) (M02A)

ArtNr ABC-AT4024a
Hersteller Abcepta
Menge 200 ul
Kategorie
Typ Antibody Primary
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen WB
Clon 4G3
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products SPINLW1, Eppin, EPPIN, WAP7, WFDC7, Cancer/testis antigen 71, CT71, Epididymal protease inhibitor, Protease inhibitor WAP7, Serine protease inhibitor-like with Kunitz and WAP domains 1, WAP four-disulfide core domain protein 7
Lieferbar
Primary Accession
O95925
Antigen Type
Recombinant Protein
Application
WB
Bio Background
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Bio References
Variants of the EPPIN gene affect the risk of idiopathic male infertility in the Han-Chinese population. Ding X, et al. Hum Reprod, 2010 Jul. PMID 20488803.Variants in the Eppin gene show association with semen quality in Han-Chinese population. Ding X, et al. Reprod Biomed Online, 2010 Jan. PMID 20158997.Analysis of recombinant human semenogelin as an inhibitor of human sperm motility. Mitra A, et al. Biol Reprod, 2010 Mar. PMID 19889947.The effect of anti-eppin antibodies on ionophore A23187-induced calcium influx and acrosome reaction of human spermatozoa. Zhang J, et al. Hum Reprod, 2010 Jan. PMID 19801569.Molecular mechanism of epididymal protease inhibitor modulating the liquefaction of human semen. Wang ZJ, et al. Asian J Androl, 2008 Sep. PMID 18645681.
Clonality
Monoclonal
Gene ID
100526773; 57119
Gene Name
EPPIN
Subtitle
Mouse monoclonal antibody raised against a partial recombinant SPINLW1.
Reactivity
H
Legend image 1
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (38.06 KDa) .
Type image 1
WB
Dilution image 1
1:500~1000
Other Accession
NM_020398
Isotype
IgM Kappa
Antigen Source
Human: ~~ Positive
Target/Specificity
SPINLW1 (NP_065131, 22 a.a. ~ 133 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession
NP_001185915.1; NP_065131.1
Clone: 4G3
Org Accession
NP_065131
Gene Description
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
Gene Summary
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ul
Lieferbar: In stock
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