SMNDC1 Antibody (monoclonal) (M01)

O75940

WB, IHC

Splicing factor Spf30 assists exosome-mediated gene silencing in fission yeast. Bernard P, et al. Mol Cell Biol, 2010 Mar. PMID 20028739.Splicing factor SPF30 bridges an interaction between the prespliceosome protein U2AF35 and tri-small nuclear ribonucleoprotein protein hPrp3. Little JT, et al. J Biol Chem, 2008 Mar 28. PMID 18211889.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Beausoleil SA, et al. Nat Biotechnol, 2006 Oct. PMID 16964243.A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Grupe A, et al. Am J Hum Genet, 2006 Jan. PMID 16385451.

10285

Mouse monoclonal antibody raised against a full length recombinant SMNDC1.

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (51.92 KDa) .

1:500~1000

WB

Immunoperoxidase of monoclonal antibody to SMNDC1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 6 ug/ml]

BC011234

Human: ~~ Positive

NP_005862.1

AAH11234

This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq