ArtNr |
ABC-AT2282a |
Hersteller |
Abcepta
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Applikationen |
WB, IP, ELISA |
Clon |
3D9 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
GSTO1, Glutathione S-transferase omega 1-1, Glutathione S-transferase omega-1, Glutathione-dependent dehydroascorbate reductase, GSTO 1-1, GSTO-1, Monomethylarsonic acid reductase, SPG-R, MMA(V) reductase, S-(Phenacyl)glutathione reductase, GSTTLP28 |
Lieferbar |
|
Primary Accession |
P78417 |
Antigen Type |
Recombinant Protein |
Application |
WB, IP, E |
Bio Background |
The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. |
Bio References |
Polymorphisms in Glutathione S-Transferase Omega-1 Gene and Increased Risk of Sporadic Alzheimer Disease. Capurso C, et al. Rejuvenation Res, 2010 Sep 6. PMID 20818931.Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism. Porter KE, et al. Environ Res, 2010 Aug. PMID 20670920.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Arsenic induces DNA damage in environmentally exposed Mexican children and adults. Influence of GSTO1 and AS3MT polymorphisms. Sampayo-Reyes A, et al. Toxicol Sci, 2010 Sep. PMID 20547570.Genetic polymorphism of As3MT and delayed urinary DMA excretion after organic arsenic intake from oyster ingestion. Hwang YH, et al. J Environ Monit, 2010 Jun. PMID 20532380. |
Clonality |
Monoclonal |
Gene ID |
9446 |
Gene Name |
GSTO1 |
Subtitle |
Mouse monoclonal antibody raised against a partial recombinant GSTO1. |
Reactivity |
H |
Legend image 1 |
Immunoprecipitation of GSTO1 transfected lysate using anti-GSTO1 monoclonal antibody and Protein A Magnetic Bead ( U0007), and immunoblotted with GSTO1 MaxPab rabbit polyclonal antibody. |
Type image 1 |
IP |
Legend image 2 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) . |
Type image 2 |
WB |
Dilution image 2 |
1:500~1000 |
Legend image 3 |
Detection limit for recombinant GST tagged GSTO1 is approximately 0.03ng/ml as a capture antibody. |
Type image 3 |
E |
Other Accession |
NM_004832 |
Isotype |
IgG1 Kappa |
Antigen Source |
Human: ~~ Positive |
Target/Specificity |
GSTO1 (NP_004823, 121 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
NCBI Accession |
NP_001177931.1; NP_001177932.1; NP_004823.1 |
|
Clone: 3D9 |
Org Accession |
NP_004823 |
Gene Description |
glutathione S-transferase omega 1 |
Gene Summary |
This gene encodes a member of the theta class glutathione S-transferase-like (GSTTL) protein family. In mouse, the encoded protein acts as a small stress response protein, likely involved in cellular redox homeostasis. [provided by RefSeq |
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