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GSTO1 Antibody (monoclonal) (M01)

GSTO1 Antibody (monoclonal) (M01)

ArtNr	ABC-AT2282a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen	WB, IP, ELISA
Clon	3D9
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GSTO1, Glutathione S-transferase omega 1-1, Glutathione S-transferase omega-1, Glutathione-dependent dehydroascorbate reductase, GSTO 1-1, GSTO-1, Monomethylarsonic acid reductase, SPG-R, MMA(V) reductase, S-(Phenacyl)glutathione reductase, GSTTLP28
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Primary Accession	P78417
Antigen Type	Recombinant Protein
Application	WB, IP, E
Bio Background	The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.
Bio References	Polymorphisms in Glutathione S-Transferase Omega-1 Gene and Increased Risk of Sporadic Alzheimer Disease. Capurso C, et al. Rejuvenation Res, 2010 Sep 6. PMID 20818931.Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism. Porter KE, et al. Environ Res, 2010 Aug. PMID 20670920.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Arsenic induces DNA damage in environmentally exposed Mexican children and adults. Influence of GSTO1 and AS3MT polymorphisms. Sampayo-Reyes A, et al. Toxicol Sci, 2010 Sep. PMID 20547570.Genetic polymorphism of As3MT and delayed urinary DMA excretion after organic arsenic intake from oyster ingestion. Hwang YH, et al. J Environ Monit, 2010 Jun. PMID 20532380.
Clonality	Monoclonal
Gene ID	9446
Gene Name	GSTO1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant GSTO1.
Reactivity	H
Legend image 1	Immunoprecipitation of GSTO1 transfected lysate using anti-GSTO1 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with GSTO1 MaxPab rabbit polyclonal antibody.
Type image 1	IP
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	Detection limit for recombinant GST tagged GSTO1 is approximately 0.03ng/ml as a capture antibody.
Type image 3	E
Other Accession	NM_004832
Isotype	IgG1 Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	GSTO1 (NP_004823, 121 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_001177931.1; NP_001177932.1; NP_004823.1
	Clone: 3D9
Org Accession	NP_004823
Gene Description	glutathione S-transferase omega 1
Gene Summary	This gene encodes a member of the theta class glutathione S-transferase-like (GSTTL) protein family. In mouse, the encoded protein acts as a small stress response protein, likely involved in cellular redox homeostasis. [provided by RefSeq

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Menge: 100 ug

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