ArtNr |
ABC-AT1962a |
Hersteller |
Abcepta
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Applikationen |
WB |
Clon |
1G12 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
EXO1, Exonuclease 1, HEX1, hExoI, Exonuclease I, hExo1, 31--, EXOI |
Lieferbar |
|
Primary Accession |
Q9UQ84 |
Antigen Type |
Recombinant Protein |
Application |
WB |
Bio Background |
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. |
Bio References |
A Large-scale genetic association study of esophageal adenocarcinoma risk. Liu CY, et al. Carcinogenesis, 2010 Jul. PMID 20453000.Delineation of WRN helicase function with EXO1 in the replicational stress response. Aggarwal M, et al. DNA Repair (Amst), 2010 Jul 1. PMID 20447876.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Single-nucleotide polymorphism of the Exo1 gene: association with gastric cancer susceptibility and interaction with smoking in Taiwan. Bau DT, et al. Chin J Physiol, 2009 Dec 31. PMID 20337148.Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA. Vallur AC, et al. PLoS One, 2010 Jan 26. PMID 20126648. |
Clonality |
Monoclonal |
Gene ID |
9156 |
Gene Name |
EXO1 |
Subtitle |
Mouse monoclonal antibody raised against a partial recombinant EXO1. |
Reactivity |
H |
Legend image 1 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) . |
Type image 1 |
WB |
Dilution image 1 |
1:500~1000 |
Legend image 2 |
EXO1 monoclonal antibody (M01), clone 1G12 Western Blot analysis of EXO1 expression in A-431 ( (Cat # AT1962a ) |
Type image 2 |
WB |
Dilution image 2 |
1:500~1000 |
Other Accession |
BC007491 |
Isotype |
IgG1 Kappa |
Antigen Source |
Human: ~~ Positive |
Target/Specificity |
EXO1 (AAH07491, 747 a.a. ~ 846 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
NCBI Accession |
NP_003677.4; NP_006018.4; NP_569082.2 |
|
Clone: 1G12 |
Org Accession |
AAH07491 |
Gene Description |
exonuclease 1 |
Gene Summary |
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq |
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