DHX9 Antibody (monoclonal) (M01)

Q08211

WB, IHC, IF

1.Roles of the Linker Region of RNA Helicase A in HIV-1 RNA Metabolism.Xing L, Niu M, Zhao X, Kleiman LPLoS One. 2013 Nov 6; 8(11):e78596. doi: 10.1371/journal.pone.0078596.2.Cellular RNA Binding Proteins NS1-BP and hnRNP K Regulate Influenza A Virus RNA Splicing.Tsai PL, Chiou NT, Kuss S, Garcia-Sastre A, Lynch KW, Fontoura BMPLoS Pathog. 2013 Jun; 9(6):e1003460. doi: 10.1371/journal.ppat.1003460. Epub 2013 Jun 27.3.In vitro and in vivo analysis of the interaction between RNA helicase A and HIV-1 RNA.Xing L, Niu M, Kleiman L.J Virol. 2012 Sep 26. [Epub ahead of print]4.Coordinate roles of Gag and RNA helicase A in promoting the annealing of tRNALys3 to HIV-1 RNA.Xing L, Liang C, Kleiman L.J Virol. 2010 Nov 24. [Epub ahead of print]5.Functional proteomic analysis of promyelocytic leukaemia nuclear bodies in irradiation-induced MCF-7 cells.Liu J, Song Y, Tian B, Qian J, Dong Y, Liu J, Liu B, Sun Z.J Biochem. 2010 Dec; 148(6):659-67. Epub 2010 Sep 7.6.RNA Helicase A Interacts with RISC in Human Cells and Functions in RISC Loading.Robb GB, Rana TM.Mol Cell. 2007 May 25; 26(4):523-37.

1660

Mouse monoclonal antibody raised against a partial recombinant DHX9.

Immunofluorescence of monoclonal antibody to DHX9 on HeLa cell. [antibody concentration 10 ug/ml]

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) .

1:500~1000

WB

Immunoperoxidase of monoclonal antibody to DHX9 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]

NM_001357

Human: ~~ Positive

NP_001348.2

NP_001348

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression. It contains 2 copies of a double-stranded RNA-binding domain, a DEXH core domain and an RGG box. The RNA-binding domains and RGG box influence and regulate RNA helicase activity. [provided by RefSeq