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ADRA1A Antibody (monoclonal) (M01)

ArtNr ABC-AT1058a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen WB, ELISA
Clon 4C7
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products ADRA1A, ADRA1C, Alpha-1A adrenergic receptor, Alpha-1A adrenoreceptor, Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c
Lieferbar
Primary Accession
P35348
Antigen Type
Recombinant Protein
Application
WB, E
Bio Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Bio References
Association between Genetic Polymorphisms of Adrenergic Receptor and Diurnal Intraocular Pressure in Japanese Normal-Tension Glaucoma. Gao Y, et al. Ophthalmology, 2010 Aug 10. PMID 20705341.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture. Herlyn P, et al. Clin J Pain, 2010 Mar-Apr. PMID 20173430.Lack of association between genetic polymorphisms affecting sympathetic activity and tilt-induced vasovagal syncope. Sorrentino S, et al. Auton Neurosci, 2010 Jun 24. PMID 20129829.
Clonality
Monoclonal
Gene ID
148
Gene Name
ADRA1A
Subtitle
Mouse monoclonal antibody raised against a partial recombinant ADRA1A.
Reactivity
H
Legend image 1
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (28.71 KDa) .
Type image 1
WB
Dilution image 1
1:500~1000
Legend image 2
ADRA1A monoclonal antibody (M01), clone 4C7 Western Blot analysis of ADRA1A expression in HL-60 ( (Cat # AT1058a )
Type image 2
WB
Dilution image 2
1:500~1000
Legend image 3
Detection limit for recombinant GST tagged ADRA1A is approximately 0.3ng/ml as a capture antibody.
Type image 3
E
Other Accession
NM_033303
Isotype
IgG1 Kappa
Antigen Source
Human: ~~ Positive
Target/Specificity
ADRA1A (NP_150646, 1 a.a. ~ 27 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession
NP_000671.2; NP_150645.2; NP_150646.3; NP_150647.2
Clone: 4C7
Org Accession
NP_150646
Gene Description
adrenergic, alpha-1A-, receptor
Gene Summary
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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