ArtNr |
ABC-AT1058a |
Hersteller |
Abcepta
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Applikationen |
WB, ELISA |
Clon |
4C7 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
ADRA1A, ADRA1C, Alpha-1A adrenergic receptor, Alpha-1A adrenoreceptor, Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c |
Lieferbar |
|
Primary Accession |
P35348 |
Antigen Type |
Recombinant Protein |
Application |
WB, E |
Bio Background |
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. |
Bio References |
Association between Genetic Polymorphisms of Adrenergic Receptor and Diurnal Intraocular Pressure in Japanese Normal-Tension Glaucoma. Gao Y, et al. Ophthalmology, 2010 Aug 10. PMID 20705341.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture. Herlyn P, et al. Clin J Pain, 2010 Mar-Apr. PMID 20173430.Lack of association between genetic polymorphisms affecting sympathetic activity and tilt-induced vasovagal syncope. Sorrentino S, et al. Auton Neurosci, 2010 Jun 24. PMID 20129829. |
Clonality |
Monoclonal |
Gene ID |
148 |
Gene Name |
ADRA1A |
Subtitle |
Mouse monoclonal antibody raised against a partial recombinant ADRA1A. |
Reactivity |
H |
Legend image 1 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (28.71 KDa) . |
Type image 1 |
WB |
Dilution image 1 |
1:500~1000 |
Legend image 2 |
ADRA1A monoclonal antibody (M01), clone 4C7 Western Blot analysis of ADRA1A expression in HL-60 ( (Cat # AT1058a ) |
Type image 2 |
WB |
Dilution image 2 |
1:500~1000 |
Legend image 3 |
Detection limit for recombinant GST tagged ADRA1A is approximately 0.3ng/ml as a capture antibody. |
Type image 3 |
E |
Other Accession |
NM_033303 |
Isotype |
IgG1 Kappa |
Antigen Source |
Human: ~~ Positive |
Target/Specificity |
ADRA1A (NP_150646, 1 a.a. ~ 27 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
NCBI Accession |
NP_000671.2; NP_150645.2; NP_150646.3; NP_150647.2 |
|
Clone: 4C7 |
Org Accession |
NP_150646 |
Gene Description |
adrenergic, alpha-1A-, receptor |
Gene Summary |
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.