Vergleich

ADAM11 Antibody (monoclonal) (M01)

ArtNr ABC-AT1041a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen WB, ELISA
Clon 3D4
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MDC, ADAM11, Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein, ADAM 11
Lieferbar
Primary Accession
O75078
Antigen Type
Recombinant Protein
Application
WB, E
Bio Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.
Bio References
A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. Fu GK, et al. Genomics, 2004 Jul. PMID 15203218.Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Brandenberger R, et al. Nat Biotechnol, 2004 Jun. PMID 15146197.An unappreciated role for RNA surveillance. Hillman RT, et al. Genome Biol, 2004. PMID 14759258.Generation and initial analysis of more than 15, 000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Clonality
Monoclonal
Gene ID
4185
Gene Name
ADAM11
Subtitle
Mouse monoclonal antibody raised against a partial recombinant ADAM11.
Reactivity
H
Legend image 1
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.18 KDa) .
Type image 1
WB
Dilution image 1
1:500~1000
Legend image 2
ADAM11 monoclonal antibody (M01), clone 3D4. Western Blot analysis of ADAM11 expression in human colon.
Type image 2
WB
Dilution image 2
1:500~1000
Legend image 3
Detection limit for recombinant GST tagged ADAM11 is approximately 0.1ng/ml as a capture antibody.
Type image 3
E
Other Accession
NM_002390
Isotype
IgG2b Kappa
Antigen Source
Human: ~~ Positive
Target/Specificity
ADAM11 (NP_002381, 230 a.a. ~ 333 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession
NP_002381.2
Clone: 3D4
Org Accession
NP_002381
Gene Description
ADAM metallopeptidase domain 11
Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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