ArtNr |
ABC-ASC11963 |
Hersteller |
Abcepta
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, IHC, ELISA |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Lieferbar |
|
Primary Accession |
Q6NUI6 |
Application |
WB, IHC, E |
Bio Background |
The Chondroadherin-like (CHADL) protein, also known as SLRR4B, is homologous to the Chondroadherin protein and is expressed cartillaginous tissues (1). Like Chondroadherin, CHADL belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1, 2). CHADL is thought to play a negative regualtory role in collagen fibrillogenesis and chondrocyte differentiation (1). |
Bio References |
Tillgren V, Ho JC, Onnerfjord P, et al. The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentitation. J. Biol. Chem. 2015; 290:918-25.Neame PJ, Sommarin Y, Boynton RE, et al. The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage. J. Biol. Chem. 1994; 269:21547-54. |
Clonality |
Polyclonal |
Gene ID |
150356 |
Gene Name |
CHADL |
Reactivity |
H, M, Rat |
Legend image 1 |
Immunofluorescence of SOX2 in mouse brain tissue with SOX2 Antibodyat 20 µg/mL. |
Type image 1 |
IF |
Other Accession |
NP_612490; 150356 |
Isotype |
IgG |
Calculated MW |
82388 |
Antigen Source |
homo sapiens |
Target/Specificity |
CHADL antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CHADL.
The immunogen is located within the last 50 amino acids of CHADL. |
Purification |
CHADL Antibody is affinity chromatography purified via peptide column. |
Reconstitution & Storage |
CHADL antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
Antibody Form |
Liquid |
Application Notes |
CHADL antibody can be used for the detection of CHADL by Western blot at 1 - 2 μ g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ g/mL. |
Positive Control |
Rat Skeletal Muscle Tissue Lysate; |
Buffer |
CHADL Antibody is supplied in PBS containing 0.02% sodium azide. |
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