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MMP9 Antibody

MMP9 Antibody

ArtNr	ABC-ASC11696
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, IF, ELISA, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Primary Accession	P14780
Application	WB, IHC-P, IF, E
Bio Background	The matrix metalloproteinase (MMP) family are a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases (1). MMP9 degrades type IV and V collagens (2) and studies suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow (3) and plays a role in tumor-associated tissue remodeling (4).
Bio References	Iyer RP, Patterson NL, Fields GB, et al. The history of matrix metalloproteinases: milestones, myths, and misperceptions. Am. J. Heart Circ. Physiol 2012; 303:H919-30. Murphy G, Knauper V, Atkinson S, et al. Matrix metalloproteinases in arthritic disease. Arthritis Res. 2002; 4 Suppl. 3:S39-49. Sweeney EA, Lortat-Jacob H, Priestley GV, et al. Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells. Blood 2002; 99:44-51. Rhee JW, Lee KW, Sohn WJ, et al. Regulation of matrix metalloproteinase-9 gene expression and cell migration by NF-kappa B in response to CpG-oligodeoxynucleotides in RAW 264.7 cells. Mol. Immunol. 2007; 44:1393-400.
Clonality	Polyclonal
Gene ID	4318
Gene Name	MMP9
Reactivity	H, M, Rat
Legend image 1	Western blot analysis of MMP9 in mouse lung tissue lysate with MMP9 antibody at 1 µg/ml.
Type image 1	WB
Legend image 2	Immunohistochemistry of MMP9 in human lung tissue with MMP9 antibody at 2.5 µg/mL.
Type image 2	IHC
Legend image 3	Immunofluorescence of MMP9 in human lung tissue with MMP9 antibody at 20 µg/mL.
Type image 3	IF
Other Accession	NP_004985; 74272287
Isotype	IgG
Calculated MW	78458
Antigen Source	homo sapiens
Target/Specificity	MMP9; MMP9 antibody is human, mouse and rat reactive. At least three isoforms of MMP9 are known to exist; this antibody only recognizes the two longest isoforms.
Purification	MMP9 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage	MMP9 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
Antibody Form	Liquid
Application Notes	MMP9 antibody can be used for detection of MMP9 by Western blot at 1 - 2 µg/ml.
Positive Control	;
Buffer	MMP9 Antibody is supplied in PBS containing 0.02% sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-ASC11696-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 100 ug

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Lieferung vsl. bis 06.09.2024

Express-Lieferung: 4 Tage sparen

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