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YPEL2 Antibody

ArtNr ABC-ASC11457
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, IF, ICC, ELISA
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Primary Accession
Q96QA6
Application
WB, IF, ICC, E
Bio Background
YPEL2 Antibody: YPEL2 (yippee-like 2) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL2 might be an important factor during the development and malignant transformation of tissues, most notably pancreatic and breast tumors.
Bio References
Hosono K, Sasaki T, Minoshima S, et al. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. Gene 2004; 340: 31-43.
Couch FJ, Wang X, Bamlet WR, et al. Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. Cancer Epidemiol. Biomarkers Prev. 2010; 19:251-7
Olson JE, Wang X, Pankratz VS, et al. Centrosome-related genes, genetic variation, and risk of breast cancer. Breast Cancer Res. Treat. 2011; 125:221-8.
Clonality
Polyclonal
Gene ID
388403
Gene Name
YPEL2
Reactivity
H, M
Legend image 1
Western blot analysis of YPEL2 in HeLa cell lysate with YPEL2 antibody at 1 µg/mL.
Type image 1
WB
Legend image 2
Immunocytochemistry of YPEL2 in HeLa cells with YPEL2 antibody at 2.5 µg/mL.
Type image 2
ICC
Legend image 3
Immunofluorescence of YPEL2 in HeLa cells with YPEL2 antibody at 5 µg/mL.
Type image 3
IF
Other Accession
EAW94407; 53292625
Isotype
IgG
Calculated MW
13577
Antigen Source
Homo sapiens
Target/Specificity
YPEL2;
Purification
YPEL2 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage
YPEL2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody Form
Liquid
Application Notes
YPEL2 antibody can be used for detection of YPEL2 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL. For immunofluorescence start at 5 µg/mL.
Positive Control
HeLa Cell Lysate;
Buffer
YPEL2 Antibody is supplied in PBS containing 0.02% sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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