MINA Antibody

Q8IUF8

MINA Antibody: MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.

Polyclonal

RIOX2 (HGNC:19441)

Western blot analysis of MINA in human heart tissue lysate with MINA antibody at (A) 1 and (B) 2 µg/mL.

Immunohistochemistry of MINA in mouse heart tissue with MINA antibody at 5 µg/mL.

Immunofluorescence of MINA in mouse heart tissue with MINA antibody at 20 µg/mL.

NP_694822; 110227621

52800

MINA;

MINA antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

MINA antibody can be used for detection of MINA by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.

MINA Antibody is supplied in PBS containing 0.02% sodium azide.