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ZBED3 Antibody

ZBED3 Antibody

ArtNr	ABC-ASC10880
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, ICC, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Primary Accession	Q96IU2
Application	WB, ICC, E
Bio Background	ZBED3 Antibody: Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.
Bio References	Chen T, Li M, Ding Y, et al. Identification of Zinc-finger BED domain containing 3 (Zbed3) as a novel axin-interacting protein that activates Wnt/b-catenin signaling. J. Biol. Chem.2009; 284:6683-9.
Clonality	Polyclonal
Gene ID	84327
Gene Name	ZBED3
Reactivity	H
Legend image 1	Western blot analysis of ZBED3 in Jurkat cell lysate with ZBED3 antibody at 1 µg/mL.
Type image 1	WB
Legend image 2	Immunocytochemistry of ZBED3 in A549 cells with ZBED3 antibody at 20 µg/mL.
Type image 2	ICC
Other Accession	NP_115743; 14150185
Isotype	IgG
Calculated MW	25132
Antigen Source	Homo sapiens
Target/Specificity	ZBED3; This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.
Purification	ZBED3 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage	ZBED3 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody Form	Liquid
Application Notes	ZBED3 antibody can be used for detection of ZBED3 by Western blot at 1 µg/mL. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. Antibody can also be used for immunocytochemistry starting at 20 µg/mL.
Positive Control	Jurkat Cell Lysate;
Buffer	ZBED3 Antibody is supplied in PBS containing 0.02% sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-ASC10880-datasheet.pdf

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Menge: 100 ug

lieferbar

Lieferung vsl. bis 04.10.2024

Express-Lieferung: 16 Tage sparen

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