ArtNr |
ABC-ASC10159 |
Hersteller |
Abcepta
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, ICC, ELISA |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
member 9, hCARD9, caspase recruitment domain family, Caspase recruitment domain-containing protein 9, CARD9 Antibody: CANDF2 |
Lieferbar |
|
Primary Accession |
Q9H257 |
Application |
WB, ICC, E |
Bio Background |
CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-κB. CARD9 is an upstream activator of BCL-10 and NF-κB signaling. |
Bio References |
Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES. CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-κ B. J Biol Chem. 2000; 275(52):41082-6. (RD0202) |
Clonality |
Polyclonal |
Gene ID |
64170 |
Gene Name |
CARD9 {ECO:0000303|PubMed:11053425, ECO:0000312|HGNC:HGNC:16391} |
Reactivity |
H |
Legend image 1 |
Western blot analysis of CARD9 expression in human MDA-MB-361 (A) and PC-3 (B) cell lysate with CARD9 antibody at 2.5 µg /ml. |
Type image 1 |
WB |
Legend image 2 |
Immunocytochemistry of CARD9 in K562 cells with CARD9 antibody at 10 µg/mL. |
Type image 2 |
ICC |
Other Accession |
AF311287; 11066983 |
Isotype |
IgG |
Calculated MW |
62241 |
Antigen Source |
Homo sapiens |
Target/Specificity |
CARD9; |
Purification |
CARD9 Antibody is affinity chromatography purified via peptide column. |
Reconstitution & Storage |
CARD9 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Antibody Form |
Liquid |
Application Notes |
CARD9 antibody can be used for detection of CARD9 by Western blot at 2.5 µg/mL. A band at approximately 59 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 µg/mL. |
Positive Control |
PC-3 Cell Lysate; MDA-MB-361 Cell Lysate; K562 Cell Lysate; |
Buffer |
CARD9 Antibody is supplied in PBS containing 0.02% sodium azide. |
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