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DAZAP2 Antibody (C-term)

DAZAP2 Antibody (C-term)

ArtNr	ABC-AP9973a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DAZAP2, KIAA0058, DAZ-associated protein 2, Deleted in azoospermia-associated protein 2
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Primary Accession	Q15038
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.
Bio References	Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009) Kim, J.E., et al. Mol. Cell. Biol. 28(2):803-813(2008) Shi, Y.W., et al. Chin. Med. J. 120(19):1659-1665(2007)
Clonality	Polyclonal
Clone/Animal Names	RB24199
Gene ID	9802
Gene Name	DAZAP2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of DAZAP2 Antibody (C-term) (Cat. #AP9973a) in A375 cell line lysates (35ug/lane). DAZAP2 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	DAZAP2 Antibody (C-term) (Cat. #AP9973a) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DAZAP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	17319
Antigen Region	111-139
Antigen Source	HUMAN
Target/Specificity	This DAZAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the C-terminal region of human DAZAP2.
NCBI Accession	NP_001129736.1; NP_001129738.1; NP_001129739.1; NP_001129740.1; NP_001129741.1; NP_055579.1

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ABC-AP9973a-datasheet.pdf

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Menge: 400 ul

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