ArtNr |
ABC-AP9393A-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
JMJD2B, KDM4B, JHDM3B, KIAA0876, Lysine-specific demethylase 4B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, 11411- |
Lieferbar |
|
Primary Accession |
O94953 |
Antigen Type |
Synthetic Peptide |
Application |
FC, IHC-P, WB |
Bio Background |
KDM4B / JMJD2B is a jumonji domain containing histone demethylase that specifically demethylates histone H3 at K9 and K36. |
Bio References |
Beyer, S., et al. J. Biol. Chem. 283(52):36542-36552(2008)Pollard, P.J., et al. Biochem. J. 416(3):387-394(2008)Katoh, Y., et al. Int. J. Mol. Med. 20(2):269-273(2007)Whetstine, J.R., et al. Cell 125(3):467-481(2006)Gray, S.G., et al. J. Biol. Chem. 280(31):28507-28518(2005) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB23110 |
Gene ID |
23030 |
Gene Name |
KDM4B |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of JMJD2B Antibody (N-term) (Cat. #AP9393a) in K562 cell line lysates (35ug/lane). JMJD2B (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded human Testis tissue reacted with JMJD2B Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Legend image 3 |
JMJD2B Antibody (N-term) (Cat. #AP9393a) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 3 |
FC |
Dilution image 3 |
1:10~50 |
Isotype |
Rabbit Ig |
Calculated MW |
121897 |
Antigen Region |
4-31 |
Antigen Source |
HUMAN |
Target/Specificity |
This JMJD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-31 amino acids from the N-terminal region of human JMJD2B. |
NCBI Accession |
NP_055830.1 |
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