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GABRA2 Antibody (C-term)

GABRA2 Antibody (C-term)

ArtNr	ABC-AP9297b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GABRA2, Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2
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Primary Accession	P47869
Antigen Type	Synthetic Peptide
Application	WB, FC, IHC-P
Bio Background	GABRA2 is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Bio References	Das, S., et.al., Stat Med 29 (11), 1250-1258 (2010) Bierut, L.J., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (11), 5082-5087 (2010) Dixon, C.I., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (5), 2289-2294 (2010)
Clonality	Polyclonal
Clone/Animal Names	RB23934
Gene ID	2555
Gene Name	GABRA2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	GABRA2 Antibody (C-term) (Cat.# AP9297b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GABRA2 antibody detected the GABRA2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	GABRA2 Antibody (C-term) (Cat. #AP9297b) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GABRA2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	GABRA2 Antibody (C-term) (Cat. #AP9297b) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	P23576; P26048; P10063
Predicted	B, M, Rat
Isotype	Rabbit Ig
Calculated MW	51326
Antigen Region	378-406
Antigen Source	HUMAN
Target/Specificity	This GABRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the C-terminal region of human GABRA2.
NCBI Accession	NP_000798.2; NP_001107647.1

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ABC-AP9297b-ev-datasheet.pdf

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Menge: 80 ul

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Lieferung vsl. bis 08.11.2024

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