ArtNr |
ABC-AP9297b-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
GABRA2, Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2 |
Lieferbar |
|
Primary Accession |
P47869 |
Antigen Type |
Synthetic Peptide |
Application |
WB, FC, IHC-P |
Bio Background |
GABRA2 is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. |
Bio References |
Das, S., et.al., Stat Med 29 (11), 1250-1258 (2010)Bierut, L.J., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (11), 5082-5087 (2010)Dixon, C.I., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (5), 2289-2294 (2010) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB23934 |
Gene ID |
2555 |
Gene Name |
GABRA2 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
GABRA2 Antibody (C-term) (Cat.# AP9297b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GABRA2 antibody detected the GABRA2 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
GABRA2 Antibody (C-term) (Cat. #AP9297b) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GABRA2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Legend image 3 |
GABRA2 Antibody (C-term) (Cat. #AP9297b) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 3 |
FC |
Dilution image 3 |
1:10~50 |
Other Accession |
P23576; P26048; P10063 |
Predicted |
B, M, Rat |
Isotype |
Rabbit Ig |
Calculated MW |
51326 |
Antigen Region |
378-406 |
Antigen Source |
HUMAN |
Target/Specificity |
This GABRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the C-terminal region of human GABRA2. |
NCBI Accession |
NP_000798.2; NP_001107647.1 |
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