ArtNr |
ABC-AP8694a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
Vimentin, VIM |
Lieferbar |
|
Primary Accession |
P08670 |
Antigen Type |
Recombinant Protein |
Application |
FC, IHC-P, WB |
Bio Background |
VIME is a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. This protein is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. |
Bio References |
Morishima, N., Genes Cells 4 (7), 401-414 (1999) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB22658 |
Gene ID |
7431 |
Gene Name |
VIM |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of VIME Antibody (Cat. #AP8694a) in A375 cell line lysates (35ug/lane). VIME (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
VIME Antibody (Cat. #AP8694a)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VIME Antibody for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Legend image 3 |
VIME Antibody (Cat. #AP8694a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 3 |
FC |
Dilution image 3 |
1:10~50 |
Isotype |
Rabbit Ig |
Calculated MW |
53652 |
Antigen Source |
HUMAN |
Target/Specificity |
This Vimentin antibody is generated from rabbits immunized with Vimentin recombinant protein. |
NCBI Accession |
NP_003371.2 |
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