ArtNr |
ABC-AP8678b-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
PARD3, PAR3, ASIP, PAR-3, CTCL tumor antigen se2-5, Partitioning defective 3 homolog, PAR3A, PARD-3, PAR3-alpha, Atypical PKC isotype-specific-interacting protein |
Lieferbar |
|
Primary Accession |
Q8TEW0 |
Antigen Type |
Synthetic Peptide |
Application |
FC, IHC-P, WB |
Bio Background |
PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain. |
Bio References |
Noda, Y., et.al., Genes Cells 6 (2), 107-119 (2001)Beausoleil, S.A., et.al., Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB21955 |
Gene ID |
56288 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of PARD3 Antibody (C-term) (Cat. #AP8678b) in mouse stomach tissue lysates (35ug/lane). PARD3 (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded human testis tissue reacted with PARD3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Legend image 3 |
PARD3 Antibody (C-term) (Cat. #AP8678b) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 3 |
FC |
Dilution image 3 |
1:10~50 |
Other Accession |
Q9Z340; Q99NH2 |
Predicted |
Rat |
Isotype |
Rabbit Ig |
Calculated MW |
151423 |
Antigen Region |
1329-1356 |
Antigen Source |
HUMAN |
Target/Specificity |
This PARD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1329-1356 amino acids from the C-terminal region of human PARD3. |
NCBI Accession |
NP_001171714.1; NP_001171715.1; NP_001171716.1; NP_001171717.1; NP_001171718.1; NP_001171719.1; NP_001171720.1; NP_001171721.1; NP_001171722.1; NP_001171723.1; NP_062565.2 |
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