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TRPM8 Antibody (Center R536)

TRPM8 Antibody (Center R536)

ArtNr	ABC-AP8181c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TRPM8, LTRPC6, TRPP8, Transient receptor potential cation channel subfamily M member 8, Long transient receptor potential channel 6, Transient receptor potential p8, Trp-p8, LTrpC-6, LTrpC6
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Primary Accession	Q7Z2W7
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.
Bio References	Tsavaler L., Cancer Res. 61:3760-3769(2001). Kiessling A., Prostate 56:270-279(2003). Bodding, M., Cell Calcium 42 (6), 618-628 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB14417
Gene ID	79054
Gene Name	TRPM8
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysate from human brain tissue lysate, using TRPM8 Antibody (Center R536)(Cat. #AP8181c). AP8181c was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of TRPM8 (arrow) using rabbit polyclonal TRPM8 Antibody (Center R536)(Cat.#AP8181c).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TRPM8 gene (Lane 2) (Origene Technologies).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with TRPM8 antibody (Center R536) (Cat.#AP8181c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	127685
Antigen Region	521-552
Antigen Source	HUMAN
Target/Specificity	This TRPM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-552 amino acids from the Central region of human TRPM8.
NCBI Accession	NP_076985.4

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ABC-AP8181c-ev-datasheet.pdf

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Menge: 80 ul

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