ArtNr |
ABC-AP8134a |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
mitochondrial, ADK2, Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}, AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}, 2743 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}, N-terminally processed {ECO:0000255|HAMAP-Rule:MF_03168}, AK2 {ECO:0000255|HAMAP-Rule:MF_03168} |
Lieferbar |
|
Primary Accession |
P54819 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. |
Bio References |
Noma, T., et al., Biochim. Biophys. Acta 1395(1):34-39 (1998).Lee, Y., et al., J. Biochem. 123(1):47-54 (1998).Lee, Y., et al., Biochem. Mol. Biol. Int. 39(4):833-842 (1996).Bruns, G.A., et al., Biochem. Genet. 15 (5-6), 477-486 (1977). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB3893 |
Gene ID |
204 |
Gene Name |
AK2 {ECO:0000255|HAMAP-Rule:MF_03168} |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
The anti-AK2 Pab (Cat. #AP8134a) is used in Western blot to detect AK2 in mouse kidney tissue lysate. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of anti-AK2 Antibody (N-term) (Cat.#AP8134a) in CEM cell line lysates (35ug/lane). AK2(arrow) was detected using the purified Pab. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Type image 3 |
IHC-P |
Dilution image 3 |
1:50~100 |
Isotype |
Rabbit Ig |
Calculated MW |
26478 |
Antigen Region |
1-30 |
Antigen Source |
HUMAN |
Target/Specificity |
This AK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AK2. |
NCBI Accession |
NP_001186128.1; NP_001616.1; NP_037543.1 |
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