Vergleich

BUB1 (BUB1a) Antibody (C-term)

ArtNr ABC-AP8058b-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products BUB1, BUB1L, Mitotic checkpoint serine/threonine-protein kinase BUB1, BUB1A, hBUB1
Lieferbar
Primary Accession
O43683
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.
Bio References
Shichiri, M., et al., Cancer Res. 62(1):13-17 (2002).
Cayrol, C., et al., Biochem. Biophys. Res. Commun. 298(5):720-730 (2002).
Nakagawa, H., et al., Oncol. Rep. 9(6):1229-1232 (2002).
Ru, H.Y., et al., Oncogene 21(30):4673-4679 (2002).
Lin, S.F., et al., Leuk. Lymphoma 43(2):385-391 (2002).
Clonality
Polyclonal
Clone/Animal Names
RB03123-03124
Gene ID
699
Gene Name
BUB1
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
BUB1A Antibody (F1058) (Cat.#AP8058b) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the BUB1A antibody detected the BUB1A protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2
IHC-P
Dilution image 2
1:50~100
Isotype
Rabbit Ig
Calculated MW
122375
Antigen Region
1043-1073
Antigen Source
HUMAN
Target/Specificity
This BUB1 (BUB1a) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1043-1073 amino acids from the C-terminal region of human BUB1 (BUB1a).
NCBI Accession
NP_004327.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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