ArtNr |
ABC-AP8041b-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
PIP4K2A, PIP5K2, PIP5K2A, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha, Diphosphoinositide kinase 2-alpha, PIP5KIII, Phosphatidylinositol 5-phosphate 4-kinase type II alpha, PI(5)P 4-kinase type II alpha, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PIP4KII-alpha, PtdIns(5)P-4-kinase isoform 2-alpha |
Lieferbar |
|
Primary Accession |
P48426 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
Phosphatidylinositol-4, 5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. TPIP5K2A is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4, 5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. The protein is a member of the phosphatidylinositol-4-phosphate 5-kinase family. |
Bio References |
Rozenvayn, N., et al., J. Biol. Chem. 278(10):8126-8134 (2003).Boronenkov, I.V., et al., J. Biol. Chem. 270(7):2881-2884 (1995).Loijens, J.C., et al., Adv. Enzyme Regul. 36, 115-140 (1996).Divecha, N., et al., Biochem. J. 309 (Pt 3), 715-719 (1995). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB1741 |
Gene ID |
5305 |
Gene Name |
|
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of anti-PIP4K2A Pab (Cat. #AP8041b) in HL60 cell lysate. PIP5K2A (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Other Accession |
Q9R0I8; O13010; O70172; NP_005019 |
Predicted |
M, Pig, Rat |
Isotype |
Rabbit Ig |
Calculated MW |
46225 |
Antigen Region |
303-335 |
Antigen Source |
HUMAN |
Target/Specificity |
This PIP4K2 Alpha (PIP4K2A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-335 amino acids from the C-terminal region of human PIP4K2 Alpha (PIP4K2A). |
NCBI Accession |
NP_005019.2 |
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