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PIP4K2 Alpha (PIP4K2A) Antibody (C-term)

PIP4K2 Alpha (PIP4K2A) Antibody (C-term)

ArtNr	ABC-AP8041b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PIP4K2A, PIP5K2, PIP5K2A, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha, Diphosphoinositide kinase 2-alpha, PIP5KIII, Phosphatidylinositol 5-phosphate 4-kinase type II alpha, PI(5)P 4-kinase type II alpha, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PIP4KII-alpha, PtdIns(5)P-4-kinase isoform 2-alpha
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Primary Accession	P48426
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Phosphatidylinositol-4, 5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. TPIP5K2A is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4, 5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. The protein is a member of the phosphatidylinositol-4-phosphate 5-kinase family.
Bio References	Rozenvayn, N., et al., J. Biol. Chem. 278(10):8126-8134 (2003). Boronenkov, I.V., et al., J. Biol. Chem. 270(7):2881-2884 (1995). Loijens, J.C., et al., Adv. Enzyme Regul. 36, 115-140 (1996). Divecha, N., et al., Biochem. J. 309 (Pt 3), 715-719 (1995).
Clonality	Polyclonal
Clone/Animal Names	RB1741
Gene ID	5305
Gene Name	PIP4K2A (HGNC:8997)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-PIP4K2A Pab (Cat. #AP8041b) in HL60 cell lysate. PIP5K2A (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	Q9R0I8; O13010; O70172; NP_005019
Predicted	M, Pig, Rat
Isotype	Rabbit Ig
Calculated MW	46225
Antigen Region	303-335
Antigen Source	HUMAN
Target/Specificity	This PIP4K2 Alpha (PIP4K2A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-335 amino acids from the C-terminal region of human PIP4K2 Alpha (PIP4K2A).
NCBI Accession	NP_005019.2

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Menge: 80 ul

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Lieferung vsl. bis 04.10.2024

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