Vergleich

PIK3R2 Antibody (Y467)

ArtNr ABC-AP8028c-ev-80ul
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen Western Blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Phosphatidylinositol 3-kinase regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, PtdIns-3-kinase regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PI3-kinase subunit p85-beta, Pt
Lieferbar
Primary Accession
O00459
Other Accession
Q63788; O08908; P23726
Antigen Type
Synthetic Peptide
Bio Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.
Bio References
Khan, N.A., et al., J. Neurovirol. 9(6):584-593 (2003).
Deregibus, M.C., et al., J. Biol. Chem. 277(28):25195-25202 (2002).
Cook, J.A., et al., J. Immunol. 169(1):254-260 (2002).
Park, I.W., et al., Blood 97(2):352-358 (2001).
Zauli, G., et al., FASEB J. 15(2):483-491 (2001).
Gene ID
5296
Gene Name
PIK3R2
Reactivity
H
Predicted
B, M, Rat
Calculated MW
81545
Antigen Region
445-474
Antigen Source
HUMAN
Target/Specificity
This PIK3R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from human PIK3R2.
NCBI Accession
NP_005018.1

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Menge: 80 ul
Lieferbar: Out of stock
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