ArtNr |
ABC-AP8009e |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
RPS6KB2, STK14B, Ribosomal protein S6 kinase beta-2, 70 kDa ribosomal protein S6 kinase 2, S6 kinase-related kinase, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta, SRK, p70 S6 kinase beta, S6K2, p70 S6KB, p70-beta, S6K-beta, S6K-beta-2, P70S6K2, p70-S6K 2, p70 S6K-beta |
Lieferbar |
|
Primary Accession |
Q9UBS0 |
Antigen Type |
Recombinant Protein |
Application |
FC, IHC-P, WB |
Bio Background |
RPS6KB2 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. |
Bio References |
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Lee-Fruman, K.K., et al., Oncogene 18(36):5108-5114 (1999).Saitoh, M., et al., Biochem. Biophys. Res. Commun. 253(2):470-476 (1998).Gout, I., et al., J. Biol. Chem. 273(46):30061-30064 (1998). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB22726 |
Gene ID |
6199 |
Gene Name |
RPS6KB2 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of RPS6KB2 Antibody (Cat. #AP8009e) in K562 cell line lysates (35ug/lane). RPS6KB2 (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded mouse brain tissue reacted with RPS6KB2 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Legend image 3 |
RPS6KB2 Antibody (Cat. #AP8009e) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 3 |
FC |
Dilution image 3 |
1:10~50 |
Isotype |
Rabbit Ig |
Calculated MW |
53455 |
Antigen Source |
HUMAN |
Target/Specificity |
This RPS6KB2 antibody is generated from rabbits immunized with human RPS6KB2 recombinant protein. |
NCBI Accession |
NP_003943.2 |
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