ArtNr |
ABC-AP7979B-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applikationen |
WB, FC, IF, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
BDNF, Brain-derived neurotrophic factor, Abrineurin |
Lieferbar |
|
Primary Accession |
P23560 |
Antigen Type |
Synthetic Peptide |
Application |
FC, IF, IHC-P, WB |
Bio Background |
BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this protein is reduced in both Alzheimer's and Huntington disease patients. This protein may play a role in the regulation of stress response and in the biology of mood disorders. |
Bio References |
Jiang, H., Clin. Chim. Acta 400 (1-2), 3-7 (2009)Liu, L., Psychiatr. Genet. 18 (6), 267-274 (2008)Dmitrzak-Weglarz, M., Pharmacogenomics 9 (11), 1595-1603 (2008) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB14839 |
Gene ID |
627 |
Gene Name |
BDNF {ECO:0000303|PubMed:28397838, ECO:0000312|HGNC:HGNC:1033} |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Confocal immunofluorescent analysis of BDNF Antibody (C-term)(Cat#AP7979b) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
Type image 1 |
IF |
Dilution image 1 |
1:10~50 |
Legend image 2 |
All lanes : Anti-BDNF Antibody (C-term) at 1:1000 dilutionLane 1: human cerebellum lysateLane 2: U-87 MG whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
Formalin-fixed and paraffin-embedded human brain reacted with BDNF Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 3 |
IHC-P |
Dilution image 3 |
1:10~50 |
Legend image 4 |
Flow cytometric analysis of CEM cells using BDNF Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 4 |
FC |
Dilution image 4 |
1:10~50 |
Other Accession |
P23363; P14082; P21237; Q95106; Q0EAB7 |
Predicted |
B, Hs, M, Pig, Rat |
Isotype |
Rabbit Ig |
Calculated MW |
27818 |
Antigen Region |
206-236 |
Antigen Source |
HUMAN |
Target/Specificity |
This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF. |
NCBI Accession |
NP_001137277.1; NP_001137278.1; NP_001137279.1; NP_001137280.1; NP_001137281.1; NP_001137282.1; NP_001137283.1; NP_001137284.1; NP_001137285.1; NP_001137286.1; NP_001137288.1; NP_001700.2; NP_733927.1; NP_733928.1 |
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