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BDNF Antibody (C-term)

BDNF Antibody (C-term)

ArtNr	ABC-AP7979B-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BDNF, Brain-derived neurotrophic factor, Abrineurin
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Primary Accession	P23560
Antigen Type	Synthetic Peptide
Application	FC, IF, IHC-P, WB
Bio Background	BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this protein is reduced in both Alzheimer's and Huntington disease patients. This protein may play a role in the regulation of stress response and in the biology of mood disorders.
Bio References	Jiang, H., Clin. Chim. Acta 400 (1-2), 3-7 (2009) Liu, L., Psychiatr. Genet. 18 (6), 267-274 (2008) Dmitrzak-Weglarz, M., Pharmacogenomics 9 (11), 1595-1603 (2008)
Clonality	Polyclonal
Clone/Animal Names	RB14839
Gene ID	627
Gene Name	BDNF {ECO:0000303\|PubMed:28397838, ECO:0000312\|HGNC:HGNC:1033}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of BDNF Antibody (C-term)(Cat#AP7979b) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	All lanes : Anti-BDNF Antibody (C-term) at 1:1000 dilution Lane 1: human cerebellum lysate Lane 2: U-87 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human brain reacted with BDNF Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Legend image 4	Flow cytometric analysis of CEM cells using BDNF Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 4	FC
Dilution image 4	1:10~50
Other Accession	P23363; P14082; P21237; Q95106; Q0EAB7
Predicted	B, Hs, M, Pig, Rat
Isotype	Rabbit Ig
Calculated MW	27818
Antigen Region	206-236
Antigen Source	HUMAN
Target/Specificity	This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF.
NCBI Accession	NP_001137277.1; NP_001137278.1; NP_001137279.1; NP_001137280.1; NP_001137281.1; NP_001137282.1; NP_001137283.1; NP_001137284.1; NP_001137285.1; NP_001137286.1; NP_001137288.1; NP_001700.2; NP_733927.1; NP_733928.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 80 ul

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