ArtNr |
ABC-AP7975B-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
FGF10, Fibroblast growth factor 10, Keratinocyte growth factor 2, FGF-10 |
Lieferbar |
|
Primary Accession |
O15520 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing. |
Bio References |
Nomura, S., Br. J. Cancer 99 (2), 305-313 (2008)Belleudi, F., Traffic 8 (12), 1854-1872 (2007)Igarashi, M., J. Biol. Chem. 273 (21), 13230-13235 (1998) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB13898 |
Gene ID |
2255 |
Gene Name |
FGF10 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of FGF10 Antibody (C-term) (Cat. #AP7975b) in mouse lung tissue lysates (35ug/lane). FGF10 (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded H.brain tissue reacted with FGF10 Antibody (C-term) (Cat#AP7975b). |
Type image 2 |
IHC-P |
Dilution image 2 |
1:100 |
Legend image 3 |
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with FGF10 antibody (C-term) (Cat.#AP7975b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 3 |
IHC-P |
Dilution image 3 |
1:10~50 |
Other Accession |
P70492; O35565 |
Predicted |
Rat |
Isotype |
Rabbit Ig |
Calculated MW |
23436 |
Antigen Region |
136-165 |
Antigen Source |
HUMAN |
Target/Specificity |
This FGF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human FGF10. |
NCBI Accession |
NP_004456.1 |
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