Vergleich

MAP2K1 Antibody (T291)

ArtNr ABC-AP7960e-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MAP2K1, MEK1, Dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAPK/ERK kinase 1, PRKMK1, MKK1, MAP kinase kinase 1, MAPKK 1, MEK 1
Lieferbar
Primary Accession
Q02750
Antigen Type
Synthetic Peptide
Application
WB, IHC-P
Bio Background
MAP2K1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Bio References
Zheng, B., et al., Blood 102(3):1019-1027 (2003).
Li, S.P., et al., Cancer Res. 63(13):3473-3477 (2003).
Zhu, X., et al., J. Neurochem. 86(1):136-142 (2003).
Fringer, J., et al., J. Biol. Chem. 278(23):20612-20617 (2003).
Witowsky, J.A., et al., J. Biol. Chem. 278(3):1403-1406 (2003).
Clonality
Polyclonal
Clone/Animal Names
RB11151
Gene ID
5604
Gene Name
MAP2K1 (HGNC:6840)
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
MAP2K1 Antibody (pT291) (Cat.# AP7960e) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MAP2K1 antibody detected the MAP2K1 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with MAP2K1 Antibody (T291) (Cat.#AP7960e), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Other Accession
Q01986; P29678; P31938; Q63980
Predicted
Ha, M, Rb, Rat
Isotype
Rabbit Ig
Calculated MW
43439
Antigen Region
270-299
Antigen Source
HUMAN
Target/Specificity
This MAP2K1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from human MAP2K1.
NCBI Accession
NP_002746.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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