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MEK1 (MAP2K1) Antibody (S218)

MEK1 (MAP2K1) Antibody (S218)

ArtNr	ABC-AP7960D
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MAP2K1, MEK1, Dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAPK/ERK kinase 1, PRKMK1, MKK1, MAP kinase kinase 1, MAPKK 1, MEK 1
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Primary Accession	Q02750
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	MAP2K1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Bio References	Zheng, B., et al., Blood 102(3):1019-1027 (2003). Li, S.P., et al., Cancer Res. 63(13):3473-3477 (2003). Zhu, X., et al., J. Neurochem. 86(1):136-142 (2003). Fringer, J., et al., J. Biol. Chem. 278(23):20612-20617 (2003). Witowsky, J.A., et al., J. Biol. Chem. 278(3):1403-1406 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB11147
Gene ID	5604
Gene Name	MAP2K1 (HGNC:6840)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-MAP2K1 Antibody at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of MAP2K1 (arrow) using rabbit polyclonal MAP2K1 Antibody (S217) (Cat.#AP7960d).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MAP2K1 gene (Lane 2) (Origene Technologies).
Type image 2	WB
Dilution image 2	1:1000
Other Accession	P36506; Q63932; P36507; Q90891; Q05116; Q01986; P29678; P31938; Q63980; Q24324
Predicted	D, Ha, M, Rb, Rat, X, C
Isotype	Rabbit Ig
Calculated MW	43439
Antigen Region	196-225
Antigen Source	HUMAN
Target/Specificity	This MEK1(MAP2K1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from human MEK1(MAP2K1).
NCBI Accession	NP_002746.1

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Menge: 400 ul

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