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MST1 Antibody (C-term)

MST1 Antibody (C-term)

ArtNr	ABC-AP7922a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MST1, Serine/threonine-protein kinase 4, Mammalian STE20-like protein kinase 1, STE20-like kinase MST1, Serine/threonine-protein kinase 4 37kDa subunit, Serine/threonine-protein kinase 4 18kDa subunit, STK4, KRS2, Serine/threonine-protein kinase Krs-2, MST-1, MST1/N, MST1/C
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Primary Accession	Q13043
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
Bio References	Cheung, W.L., et al., Cell 113(4):507-517 (2003). Lin, Y., et al., J. Biol. Chem. 277(50):47991-48001 (2002). De Souza, P.M., et al., Blood 99(9):3432-3438 (2002). Ura, S., et al., Proc. Natl. Acad. Sci. U.S.A. 98(18):10148-10153 (2001). Taylor, L.K., et al., Proc. Natl. Acad. Sci. U.S.A. 93(19):10099-10104 (1996).
Clonality	Polyclonal
Clone/Animal Names	RB1193
Gene ID	6789
Gene Name	STK4
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-MST1 Pab (Cat. #AP7922a) in HL60 cell lysate. MST1 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of STK4 (arrow) using MST1 Antibody (C-term) (Cat.#AP7922a).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the STK4 gene (Lane 2) (Origene Technologies).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 3	IHC-P
Dilution image 3	1:50~100
Other Accession	Q5E9L6
Predicted	B
Isotype	Rabbit Ig
Calculated MW	55630
Antigen Region	385-415
Antigen Source	HUMAN
Target/Specificity	This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the C-terminal region of human MST1.
NCBI Accession	NP_006273.1

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Menge: 80 ul

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Lieferung vsl. bis 08.11.2024

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