FKBP1A Antibody (N-term)

Synthetic Peptide

FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Polyclonal

2280

Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of FKBP1A antibody (N-term) (Cat.# AP7756a) in mouse cerebellum tissue lysates, HepG2 and Jurkat cell line lysates (35ug/lane). FKBP1A (arrow) was detected using the purified Pab.

1:1000

WB

FKBP1A Antibody (N-term) (Cat.# AP7756a) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP1A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

1:50~100

FC

P62943; P26883; P18203

Rabbit Ig

1-30

This FKBP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FKBP1A.