ArtNr |
ABC-AP7605a |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
LUM, Lumican, LDC, SLRR2D, Keratan sulfate proteoglycan lumican, KSPG lumican |
Lieferbar |
|
Primary Accession |
P51884 |
Antigen Type |
Synthetic Peptide |
Application |
FC, IHC-P, WB |
Bio Background |
LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. |
Bio References |
Wang, P., Li, S. Invest. Ophthalmol. Vis. Sci. 50 (4), 1546-1551 (2009)Matsuda, Y., Yamamoto, T. Int. J. Oncol. 33 (6), 1177-1185 (2008)Kelemen, L.E., Couch, F.J. Breast Cancer Res. 10 (6), R98 (2008) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB18422 |
Gene ID |
4060 |
Gene Name |
LUM |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of LUM Antibody (N-term) (Cat.#AP7605a) in mouse bladder tissue lysates (35ug/lane). LUM (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with LUM Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Legend image 3 |
LUM Antibody (N-term) (Cat. #AP7605a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 3 |
FC |
Dilution image 3 |
1:10~50 |
Other Accession |
P51886; P51885 |
Predicted |
Rat |
Isotype |
Rabbit Ig |
Calculated MW |
38429 |
Antigen Region |
64-91 |
Antigen Source |
HUMAN |
Target/Specificity |
This LUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-91 amino acids from the N-terminal region of human LUM. |
NCBI Accession |
NP_002336.1 |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.