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Aurora-C Antibody (N-term G11)

Aurora-C Antibody (N-term G11)

ArtNr	ABC-AP7000F-ev-80ul
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Antibodies Blastoma Carcinoma Hematology Leukemia Myeloma Melanoma Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Aurora kinase C, Aurora 3, Aurora/IPL1-related kinase 3, ARK-3, Aurora-related kinase 3, Aurora/IPL1/Eg2 protein 2, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase aurora-C, AURKC, AIE2, AIK3, AIRK3, ARK3, STK13
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Primary Accession	Q9UQB9
Antigen Type	Synthetic Peptide
Bio Background	Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Bio References	Kimura, M., et al., J. Biol. Chem. 274(11):7334-7340 (1999). Tseng, T.C., et al., DNA Cell Biol. 17(10):823-833 (1998). Bernard, M., et al., Genomics 53(3):406-409 (1998).
Gene ID	6795
Gene Name	AURKC
Reactivity	H
Calculated MW	35591
Antigen Region	1-30
Antigen Source	HUMAN
Target/Specificity	This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Aurora-C.
NCBI Accession	NP_001015878.1; NP_001015879.1; NP_003151.2

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Menge: 80 ul

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