ArtNr |
ABC-AP6799a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
HLA-DRA, HLA-DRA1, HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA |
Lieferbar |
|
Primary Accession |
P01903 |
Antigen Type |
Synthetic Peptide |
Application |
WB, FC, IHC-P |
Bio Background |
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). |
Bio References |
De Jager, et.al., Nat. Genet. 41 (7), 776-782 (2009) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB19526 |
Gene ID |
3122 |
Gene Name |
HLA-DRA |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of HLA-DRA Antibody (N-term) (Cat. #AP6799a) in Ramos cell line lysates (35ug/lane). HLA-DRA (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
HLA-DRA Antibody (N-term) (Cat. #AP6799a) IHC analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HLA-DRA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Legend image 3 |
HLA-DRA Antibody (N-term) (Cat. #AP6799a) flow cytometry analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 3 |
FC |
Dilution image 3 |
1:10~50 |
Isotype |
Rabbit Ig |
Calculated MW |
28621 |
Antigen Region |
48-75 |
Antigen Source |
HUMAN |
Target/Specificity |
This HLA-DRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-75 amino acids from the N-terminal region of human HLA-DRA. |
NCBI Accession |
NP_061984.2 |
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