ArtNr |
ABC-AP6795A-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CNN1, smooth muscle, Calponin-1, Basic calponin, Calponin H1 |
Lieferbar |
|
Primary Accession |
P51911 |
Antigen Type |
Synthetic Peptide |
Application |
WB, FC, IHC-P |
Bio Background |
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). |
Bio References |
Marsh, W.L., et.al., Appl. Immunohistochem. Mol. Morphol. 17 (3), 216-219 (2009) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB19472 |
Gene ID |
1264 |
Gene Name |
CNN1 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of Calponin-1 Antibody (N-term) (Cat. #AP6795a) in NCI-H460 cell line lysates (35ug/lane). CNN1 (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of lysates from Hela, MDA-MB-453 cell line (from left to right), using Calponin-1 Antibody (N-term)(Cat. #AP6795a). AP6795a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
Formalin-fixed and paraffin-embedded human lung carcinoma with Calponin-1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 3 |
IHC-P |
Dilution image 3 |
1:10~50 |
Legend image 4 |
Flow cytometric analysis of NCI-H292 cells using Calponin-1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 4 |
FC |
Dilution image 4 |
1:10~50 |
Other Accession |
Q08290; Q08091; Q2HJ38; Q7YRL2 |
Predicted |
B, M, Rat, Sh |
Isotype |
Rabbit Ig |
Calculated MW |
33170 |
Antigen Region |
10-39 |
Antigen Source |
HUMAN |
Target/Specificity |
This Calponin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human Calponin-1. |
NCBI Accession |
NP_001290.2 |
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