DJ-1 Antibody (N-term)

Synthetic Peptide

Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 40 years, slow progression and initial good response to levodopa.

Polyclonal

11315

Purified Rabbit Polyclonal Antibody (Pab)

Confocal immunofluorescent analysis of DJ-1 Antibody (N-term)(Cat#AP6407a) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

1:10~50

WB

All lanes : Anti-Park7 (DJ-1) N-term at 1:2000 dilution
Lane 1: Hela whole cell lysate
Lane 2: NIH/3T3 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 20 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:2000

B, Zf

19891

HUMAN

NP_001116849.1; NP_009193.2