ArtNr |
ABC-AP6177a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
MAGED2, BCG1, Melanoma-associated antigen D2, 11B6, Breast cancer-associated gene 1 protein, Hepatocellular carcinoma-associated protein JCL-1, MAGE-D2 antigen, BCG-1 |
Lieferbar |
|
Primary Accession |
Q9UNF1 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
MAGED2 is a member of the MAGED gene family. In contrast to the MAGEA and MAGEB genes, which have their entire coding sequences located in the last exon, the MAGED genes have their coding sequences located throughout multiple exons. Also, the MAGEA and MAGEB genes are silent in normal tissues with the exception of testis and placenta, whereas the MAGED genes are expressed ubiquitously. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). |
Bio References |
Lucas, S., et al., Cancer Res. 59(16):4100-4103 (1999).Langnaese, K., et al., Cytogenet. Cell Genet. 94 (3-4), 233-240 (2001). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB2127 |
Gene ID |
10916 |
Gene Name |
MAGED2 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
The anti-MAGED2 C-term Antibody (Cat.#AP6177a) is used in Western blot to detect MAGED2 in A549 lysate. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Isotype |
Rabbit Ig |
Calculated MW |
64954 |
Antigen Region |
576-606 |
Antigen Source |
HUMAN |
Target/Specificity |
This MAGED2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-606 amino acids from the C-terminal region of human MAGED2. |
NCBI Accession |
NP_055414.2; NP_803182.1; NP_957516.1 |
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