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TNIP3 Antibody (N-term)

ArtNr ABC-AP5598A-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products ABIN3, ABIN-3, LIND, A20-binding inhibitor of NF-kappa-B activation 3, TNFAIP3-interacting protein 3, Listeria-induced gene protein, TNIP3 (HGNC:19315)
Lieferbar
Primary Accession
Q96KP6
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. It Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Bio References
Folco, E.J., et al. J. Biol. Chem. 284(38):25569-25575(2009)
Verstrepen, L., et al. Biochem. Pharmacol. 78(2):105-114(2009)
Wullaert, A., et al. J. Biol. Chem. 282(1):81-90(2007)
Staege, H., et al. Immunogenetics 53(2):105-113(2001)
Clonality
Polyclonal
Clone/Animal Names
RB27057
Gene ID
79931
Gene Name
TNIP3 (HGNC:19315)
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
TNIP3 Antibody (N-term) (Cat. #AP5598a) western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the TNIP3 antibody detected the TNIP3 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
TNIP3 Antibody (N-term) (Cat. #AP5598a) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNIP3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:50~100
Other Accession
NP_001122315.1; NP_079149.3
Isotype
Rabbit Ig
Calculated MW
38943
Antigen Region
74-102
Antigen Source
HUMAN
Target/Specificity
This TNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human TNIP3.
NCBI Accession
NP_001122315.2; NP_001231693.1; NP_079149.3

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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