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DCLRE1B Antibody (Center)

DCLRE1B Antibody (Center)

ArtNr	ABC-AP5426c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DCLRE1B, 5' exonuclease Apollo, 31--, SNM1B, DNA cross-link repair 1B protein, SNM1 homolog B, SNMIB, hSNM1B
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Primary Accession	Q9H816
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).
Bio References	Anders, M., et al. Cell Cycle 8(11):1725-1732(2009) Liu, L., et al. Cell Cycle 8(4):628-638(2009) Freibaum, B.D., et al. J. Biol. Chem. 283(35):23671-23676(2008) Bae, J.B., et al. Oncogene 27(37):5045-5056(2008) Demuth, I., et al. DNA Repair (Amst.) 7(8):1192-1201(2008) Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Lenain, C., et al. Curr. Biol. 16(13):1303-1310(2006) Freibaum, B.D., et al. J. Biol. Chem. 281(22):15033-15036(2006) Ishiai, M., et al. Mol. Cell. Biol. 24(24):10733-10741(2004) Demuth, I., et al. Oncogene 23(53):8611-8618(2004) Dronkert, M.L., et al. Mol. Cell. Biol. 20(13):4553-4561(2000)
Clonality	Polyclonal
Clone/Animal Names	RB26835
Gene ID	64858
Gene Name	DCLRE1B
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	DCLRE1B Antibody (Center)(Cat. #AP5426c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the DCLRE1B antibody detected DCLRE1B protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	DCLRE1B Antibody (Center) (Cat. #AP5426c) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCLRE1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_073747.1
Isotype	Rabbit Ig
Calculated MW	60002
Antigen Region	208-236
Antigen Source	HUMAN
Target/Specificity	This DCLRE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-236 amino acids from the Central region of human DCLRE1B.
NCBI Accession	NP_073747.1

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