ArtNr |
ABC-AP3663a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
Dot |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CD130, IL6ST, Interleukin-6 receptor subunit beta, CDw130, Interleukin-6 signal transducer, Membrane glycoprotein 130, Oncostatin-M receptor subunit alpha, gp130, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB |
Lieferbar |
|
Primary Accession |
P40189 |
Antigen Type |
Synthetic Peptide |
Application |
DB |
Bio Background |
IL6ST is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. |
Bio References |
Lehmann, U., et.al., J. Biol. Chem. 278 (1), 661-671 (2003)Novotny-Diermayr, V., et.al., J. Biol. Chem. 277 (51), 49134-49142 (2002) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB21495 |
Gene ID |
3572 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Dot blot analysis of anti-Phospho-IL6ST-Y905 Phospho-specific Pab (Cat. #AP3663a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
Type image 1 |
DB |
Dilution image 1 |
1:500 |
Isotype |
Rabbit Ig |
Calculated MW |
103537 |
Antigen Source |
HUMAN |
Target/Specificity |
This IL6ST Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y905 of human IL6ST. |
NCBI Accession |
NP_001177910.1; NP_002175.2; NP_786943.1 |
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