ArtNr |
ABC-AP3563a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
Dot |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
TEK, TIE2, VMCM, VMCM1, Angiopoietin-1 receptor, Endothelial tyrosine kinase, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains-2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK, CD202b, hTIE2 |
Lieferbar |
|
Primary Accession |
Q02763 |
Antigen Type |
Synthetic Peptide |
Application |
DB |
Bio Background |
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. |
Bio References |
Cascone, I., et al., Blood 102(7):2482-2490 (2003).DeBusk, L.M., et al., Arthritis Rheum. 48(9):2461-2471 (2003).Poncet, S., et al., Neuropathol Appl Neurobiol 29(4):361-369 (2003).Lee, H.J., et al., Biochem. Biophys. Res. Commun. 304(2):399-404 (2003).Sussman, L.K., et al., Cancer Biol. Ther. 2(3):255-256 (2003). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB15213 |
Gene ID |
7010 |
Gene Name |
TEK |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Dot blot analysis of anti-Phospho-TEK-pY1113 Antibody (Cat.#AP3563a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
Type image 1 |
DB |
Dilution image 1 |
1:500 |
Other Accession |
Q02858; O73791; Q06807 |
Predicted |
B, Zf, M |
Isotype |
Rabbit Ig |
Calculated MW |
125830 |
Antigen Source |
HUMAN |
Target/Specificity |
This TEK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK. |
NCBI Accession |
NP_000450.2 |
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