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Phospho-RB(S612) Antibody

Phospho-RB(S612) Antibody

ArtNr	ABC-AP3236a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Rb, RB1, Retinoblastoma-associated protein, p105-Rb, pRb, pp110
Lieferbar
Primary Accession	P06400
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.[supplied by OMIM].
Bio References	Dasgupta, P., et al., Mol. Cell. Biol. 24(21):9527-9541 (2004). Cui, X., et al., Hum. Pathol. 35(10):1189-1195 (2004). Borah, S., et al., J. Virol. 78(19):10336-10347 (2004). Dasgupta, P., et al., J. Biol. Chem. 279(37):38762-38769 (2004). Lohmann, D.R., et al., J. Biol. Chem. 129(1):23-28 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB7659
Gene ID	5925
Gene Name	RB1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysates from NIH/3T3 cell line, untreated or treated with UV(2h), using Phospho-RB(S612) Antibody(upper) or Tubulin (lower).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of lysates from Hela cell line, untreated or treated with UV(2h), using Phospho-RB(S612) Antibody(upper) or Tubulin (lower).
Type image 2	WB
Dilution image 2	1:500
Legend image 3	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma
Type image 3	IHC-P
Dilution image 3	1:50~100
Isotype	Rabbit Ig
Calculated MW	106159
Antigen Source	HUMAN
Target/Specificity	This RB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S612 of human RB.
NCBI Accession	NP_000312.2

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Menge: 80 ul

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