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HSD17B10 Antibody (N-Term)

HSD17B10 Antibody (N-Term)

ArtNr	ABC-AP22244a-ev-50ul
Hersteller	Abcepta
Menge	50 ul
Kategorie	Neuroscience Metabolism Diabetes Neural Mitochondrial Function Antibodies Flow Cytometry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	Immunofluorescence, Western Blot, Flow cytometry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	3-hydroxyacyl-CoA dehydrogenase type-2, 1.1.1.35, 17-beta-hydroxysteroid dehydrogenase 10, 17-beta-HSD 10, 1.1.1.51, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 1.1.1.178, 3-hydroxyacyl-CoA dehydrogenase type II, Endoplasmic reticulum-associated amyloid
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Primary Accession	Q99714
Antigen Type	Synthesized Peptide
Bio Background	Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Bio References	Yan S.D., et al.Nature 389:689-695(1997). Zhuchenko O.P., et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases. Miller A.P., et al.Proc. Natl. Acad. Sci. U.S.A. 95:8709-8714(1998). He X.Y., et al.J. Biol. Chem. 273:10741-10746(1998). Ebert L., et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Gene ID	3028
Gene Name	HSD17B10
Reactivity	H
Calculated MW	26923
Antigen Source	HUMAN
Target/Specificity	This HSD17B10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 14-48 amino acids from human HSD17B10.

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Menge: 50 ul

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